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Developmental scRNAseq Trajectories in Gene- and Cell-State Space—The Flatworm Example

Single-cell RNA sequencing has become a standard technique to characterize tissue development. Hereby, cross-sectional snapshots of the diversity of cell transcriptomes were transformed into (pseudo-) longitudinal trajectories of cell differentiation using computational methods, which are based on s...

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Detalles Bibliográficos
Autores principales: Schmidt, Maria, Loeffler-Wirth, Henry, Binder, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603055/
https://www.ncbi.nlm.nih.gov/pubmed/33081343
http://dx.doi.org/10.3390/genes11101214