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Genome-Wide Gene Expression Analyses of BRCA1- and BRCA2-Associated Breast and Ovarian Tumours

SIMPLE SUMMARY: Variants in the breast cancer susceptibility genes BRCA1 and BRCA2 increase the risk of developing breast and ovarian cancers. Over the past two decades researchers have aimed to identify gene expression changes associated with high-risk BRCA1 and BRCA2 variants. In this review we ex...

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Detalles Bibliográficos
Autores principales: Wiggins, George A. R., Walker, Logan C., Pearson, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603076/
https://www.ncbi.nlm.nih.gov/pubmed/33081408
http://dx.doi.org/10.3390/cancers12103015