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A Small-RNA-Mediated Feedback Loop Maintains Proper Levels of 22G-RNAs in C. elegans

RNA interference (RNAi) is an essential regulatory mechanism in all animals. In Caenorhabditis elegans, several classes of small RNAs act to silence or license expression of mRNA targets. ERI-6/7 is required for the production of some endogenous small interfering RNAs (siRNAs) and acts as a negative...

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Detalles Bibliográficos
Autores principales: Rogers, Alicia K., Phillips, Carolyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603289/
https://www.ncbi.nlm.nih.gov/pubmed/33086057
http://dx.doi.org/10.1016/j.celrep.2020.108279