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Oncogenic action of the exosome cofactor RBM7 by stabilization of CDK1 mRNA in breast cancer

RNA exosome can target the specific RNAs for their processing/degradation by distinct exosome cofactors. As a key component in exosome cofactors, RNA binding motif protein 7 (RBM7) shows the binding specificity for uridine-rich sequences in mRNAs via its RNA recognition motifs. However, the specific...

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Detalles Bibliográficos
Autores principales: Xi, Pei-Wen, Zhang, Xu, Zhu, Lei, Dai, Xin-Yuan, Cheng, Lin, Hu, Yue, Shi, Liang, Wei, Ji-Fu, Ding, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603334/
https://www.ncbi.nlm.nih.gov/pubmed/33145401
http://dx.doi.org/10.1038/s41523-020-00200-w