Airway delivery of both a BCG prime and adenoviral boost drives CD4 and CD8 T cells into the lung tissue parenchyma

Heterologous BCG prime-boost regimens represent a promising strategy for an urgently required improved tuberculosis vaccine. Identifying the mechanisms which underpin the enhanced protection induced by such strategies is one key aim which would significantly accelerate rational vaccine development....

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Detalles Bibliográficos
Autores principales: Kaveh, Daryan A., Garcia-Pelayo, M. Carmen, Bull, Naomi C., Sanchez-Cordon, Pedro J., Spiropoulos, John, Hogarth, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603338/
https://www.ncbi.nlm.nih.gov/pubmed/33127956
http://dx.doi.org/10.1038/s41598-020-75734-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603338/
https://www.ncbi.nlm.nih.gov/pubmed/33127956
http://dx.doi.org/10.1038/s41598-020-75734-x

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