Hepcidin overexpression in astrocytes alters brain iron metabolism and protects against amyloid-β induced brain damage in mice

Progressive iron accumulation in the brain and iron-induced oxidative stress are considered to be one of the initial causes of Alzheimer’s disease (AD), and modulation of brain iron level shows promise for its treatment. Hepcidin expressed by astrocytes has been speculated to regulate iron transport...

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Detalles Bibliográficos
Autores principales: Zhang, Xinwei, Gou, Yu-Jing, Zhang, Yating, Li, Jie, Han, Kang, Xu, Yong, Li, Haiyan, You, Lin-Hao, Yu, Peng, Chang, Yan-Zhong, Gao, Guofen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603348/
https://www.ncbi.nlm.nih.gov/pubmed/33298837
http://dx.doi.org/10.1038/s41420-020-00346-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603348/
https://www.ncbi.nlm.nih.gov/pubmed/33298837
http://dx.doi.org/10.1038/s41420-020-00346-3

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