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Stress-sensing in the human greying hair follicle: Ataxia Telangiectasia Mutated (ATM) depletion in hair bulb melanocytes in canities-prone scalp

Canities (or hair greying) is an age-linked loss of the natural pigment called melanin from hair. While the specific cause(s) underlying the loss of melanogenically-active melanocytes from the anagen hair bulbs of affected human scalp remains unclear, oxidative stress sensing appears to be a key fac...

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Detalles Bibliográficos
Autores principales: Sikkink, Stephen K., Mine, Solene, Freis, Olga, Danoux, Louis, Tobin, Desmond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603349/
https://www.ncbi.nlm.nih.gov/pubmed/33128003
http://dx.doi.org/10.1038/s41598-020-75334-9