Expression of POU2F3 Transcription Factor Control Inflammation, Immunological Recruitment and Metastasis of Pancreatic Cancer in Mice

SIMPLE SUMMARY: The presence and the role of TUFT cells in pancreatic ductal adenocarcinoma (PDAC) is discussed. Therefore, we decided to inactivate the POU2F3 gene, which is essential for TUFT cells development, in an aggressive PDAC mice model known as PDX1-Cre;LSL-Kras(G12D);Ink4a(fl/fl). Morphol...

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Detalles Bibliográficos
Autores principales: Bintz, Jennifer, Abuelafia, Analía Meilerman, Gerbe, François, Baudoin, Elodie, Auphan-Anezin, Nathalie, Sidot, Emmanuelle, Jay, Philippe, Iovanna, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603360/
https://www.ncbi.nlm.nih.gov/pubmed/33086657
http://dx.doi.org/10.3390/biology9100341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603360/
https://www.ncbi.nlm.nih.gov/pubmed/33086657
http://dx.doi.org/10.3390/biology9100341

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