Tracking a TGF-β activator in vivo: sensitive PET imaging of αvβ8-integrin with the Ga-68-labeled cyclic RGD octapeptide trimer Ga-68-Triveoctin

PURPOSE: As a major activator of transforming growth factor β (TGF-β), the RGD receptor αvβ8-integrin is involved in pathogenic processes related to TGF-β dysregulation, such as tumor growth, invasion, and radiochemoresistance, metastasis and tumor cell stemness, as well as epithelial-mesenchymal tr...

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Detalles Bibliográficos
Autores principales: Quigley, Neil Gerard, Steiger, Katja, Richter, Frauke, Weichert, Wilko, Hoberück, Sebastian, Kotzerke, Jörg, Notni, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603442/
https://www.ncbi.nlm.nih.gov/pubmed/33128636
http://dx.doi.org/10.1186/s13550-020-00706-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603442/
https://www.ncbi.nlm.nih.gov/pubmed/33128636
http://dx.doi.org/10.1186/s13550-020-00706-1

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