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A novel human pluripotent stem cell-based assay to predict developmental toxicity

There is a great need for novel in vitro methods to predict human developmental toxicity to comply with the 3R principles and to improve human safety. Human-induced pluripotent stem cells (hiPSC) are ideal for the development of such methods, because they are easy to retrieve by conversion of adult...

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Detalles Bibliográficos
Autores principales: Lauschke, Karin, Rosenmai, Anna Kjerstine, Meiser, Ina, Neubauer, Julia Christiane, Schmidt, Katharina, Rasmussen, Mikkel Aabech, Holst, Bjørn, Taxvig, Camilla, Emnéus, Jenny Katarina, Vinggaard, Anne Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603451/
https://www.ncbi.nlm.nih.gov/pubmed/32700165
http://dx.doi.org/10.1007/s00204-020-02856-6