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Synthesis and in vitro characterization of the genotoxic, mutagenic and cell-transforming potential of nitrosylated heme

Data from epidemiological studies suggest that consumption of red and processed meat is a factor contributing to colorectal carcinogenesis. Red meat contains high amounts of heme, which in turn can be converted to its nitrosylated form, NO-heme, when adding nitrite-containing curing salt to meat. NO...

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Detalles Bibliográficos
Autores principales: Kostka, Tina, Fohrer, Jörg, Guigas, Claudia, Briviba, Karlis, Seiwert, Nina, Fahrer, Jörg, Steinberg, Pablo, Empl, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603461/
https://www.ncbi.nlm.nih.gov/pubmed/32671443
http://dx.doi.org/10.1007/s00204-020-02846-8