A workflow to build PBTK models for novel species

Physiology-based pharmacokinetic and toxicokinetic (PBPK/TK) models allow us to simulate the concentration of xenobiotica in the plasma and different tissues of an organism. PBPK/TK models are therefore routinely used in many fields of life sciences to simulate the physiological concentration of exo...

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Detalles Bibliográficos
Autores principales: Schneckener, Sebastian, Preuss, Thomas G., Kuepfer, Lars, Witt, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
In Silico
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603467/
https://www.ncbi.nlm.nih.gov/pubmed/33033842
http://dx.doi.org/10.1007/s00204-020-02922-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603467/
https://www.ncbi.nlm.nih.gov/pubmed/33033842
http://dx.doi.org/10.1007/s00204-020-02922-z

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