The biologically functional identification of a novel TIM3-binding peptide P26 in vitro and in vivo

PURPOSE: Recent studies have shown that TIM3 plays an important role in T-cell failure, which is closely related to the resistance to anti-programmed cell death protein 1 (PD-1) treatment. However, there have been no reports on the application of peptide blockers to TIM3. In this study, we endeavore...

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Detalles Bibliográficos
Autores principales: Zhong, Tangwu, Zhao, Chuanke, Wang, Shuntao, Tao, Deshuang, Ma, Shuxia, Shou, Chengchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603469/
https://www.ncbi.nlm.nih.gov/pubmed/33084973
http://dx.doi.org/10.1007/s00280-020-04167-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603469/
https://www.ncbi.nlm.nih.gov/pubmed/33084973
http://dx.doi.org/10.1007/s00280-020-04167-0

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