Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause

The epiblast, which provides the foundation of the future body, is actively reshaped during early embryogenesis, but the reshaping mechanisms are poorly understood. Here, using a 3D in vitro model of early epiblast development, we identify the canonical Wnt/β-catenin pathway and its central downstre...

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Detalles Bibliográficos
Autores principales: Fan, Rui, Kim, Yung Su, Wu, Jie, Chen, Rui, Zeuschner, Dagmar, Mildner, Karina, Adachi, Kenjiro, Wu, Guangming, Galatidou, Styliani, Li, Jianhua, Schöler, Hans R., Leidel, Sebastian A., Bedzhov, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603494/
https://www.ncbi.nlm.nih.gov/pubmed/33127892
http://dx.doi.org/10.1038/s41467-020-19353-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603494/
https://www.ncbi.nlm.nih.gov/pubmed/33127892
http://dx.doi.org/10.1038/s41467-020-19353-0

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