Cargando…

RING-finger protein 166 plays a novel pro-apoptotic role in neurotoxin-induced neurodegeneration via ubiquitination of XIAP

The dopaminergic neurotoxin, 6-hydroxydopamine (6-OHDA), has been widely utilized to establish experimental models of Parkinson disease and to reveal the critical molecules and pathway underlying neuronal death. The profile of gene expression changes following 6-OHDA treatment of MN9D dopaminergic n...

Descripción completa

Detalles Bibliográficos
Autores principales: Oh, Chang-Ki, Choi, Young Ki, Hwang, Ih-Yeon, Ko, Yeon Uk, Chung, In Kwon, Yun, Nuri, Oh, Young J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603511/
https://www.ncbi.nlm.nih.gov/pubmed/33130818
http://dx.doi.org/10.1038/s41419-020-03145-x