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Nonalcoholic Fatty Liver Disease Impairs the Liver–Alpha Cell Axis Independent of Hepatic Inflammation and Fibrosis

Nonalcoholic fatty liver disease (NAFLD) is associated with impaired hepatic actions of glucagon and insulin. Glucagon and amino acids are linked in an endocrine feedback circuit, the liver–alpha cell axis, that may be disrupted by NAFLD. We investigated how NAFLD severity affects glucagon and insul...

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Detalles Bibliográficos
Autores principales: Pedersen, Julie Steen, Rygg, Marte Opseth, Kristiansen, Viggo Bjerregaard, Olsen, Beth Hærstedt, Serizawa, Reza Rafiolsadat, Holst, Jens Juul, Madsbad, Sten, Gluud, Lise Lotte, Bendtsen, Flemming, Wewer Albrechtsen, Nicolai Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603528/
https://www.ncbi.nlm.nih.gov/pubmed/33163832
http://dx.doi.org/10.1002/hep4.1562