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Nonalcoholic Fatty Liver Disease Impairs the Liver–Alpha Cell Axis Independent of Hepatic Inflammation and Fibrosis
Nonalcoholic fatty liver disease (NAFLD) is associated with impaired hepatic actions of glucagon and insulin. Glucagon and amino acids are linked in an endocrine feedback circuit, the liver–alpha cell axis, that may be disrupted by NAFLD. We investigated how NAFLD severity affects glucagon and insul...
Autores principales: | Pedersen, Julie Steen, Rygg, Marte Opseth, Kristiansen, Viggo Bjerregaard, Olsen, Beth Hærstedt, Serizawa, Reza Rafiolsadat, Holst, Jens Juul, Madsbad, Sten, Gluud, Lise Lotte, Bendtsen, Flemming, Wewer Albrechtsen, Nicolai Jacob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603528/ https://www.ncbi.nlm.nih.gov/pubmed/33163832 http://dx.doi.org/10.1002/hep4.1562 |
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