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Hyperglycemia Induces Endoplasmic Reticulum Stress in Atrial Cardiomyocytes, and Mitofusin-2 Downregulation Prevents Mitochondrial Dysfunction and Subsequent Cell Death

Mitochondrial oxidative stress and dysfunction play an important role of atrial remodeling and atrial fibrillation (AF) in diabetes mellitus. Endoplasmic reticulum (ER) stress has been linked to both physiological and pathological states including diabetes. The aim of this project is to explore the...

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Detalles Bibliográficos
Autores principales: Yuan, Ming, Gong, Mengqi, Zhang, Zhiwei, Meng, Lei, Tse, Gary, Zhao, Yungang, Bao, Qiankun, Zhang, Yue, Yuan, Meng, Liu, Xing, Li, Guangping, Liu, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603626/
https://www.ncbi.nlm.nih.gov/pubmed/33149811
http://dx.doi.org/10.1155/2020/6569728