Effect of APOE ε4 genotype on amyloid-β and tau accumulation in Alzheimer’s disease

BACKGROUND: To assess the effects of apolipoprotein E (ApoE) ε4 genotype on amyloid-β (Aβ) and tau burden and their longitudinal changes in Alzheimer’s disease (AD) spectrum. METHODS: Among 272 individuals who underwent PET scans ((18)F-florbetaben for Aβ and (18)F-flortaucipir for tau) and ApoE gen...

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Detalles Bibliográficos
Autores principales: Baek, Min Seok, Cho, Hanna, Lee, Hye Sun, Lee, Jae Hoon, Ryu, Young Hoon, Lyoo, Chul Hyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603688/
https://www.ncbi.nlm.nih.gov/pubmed/33129364
http://dx.doi.org/10.1186/s13195-020-00710-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603688/
https://www.ncbi.nlm.nih.gov/pubmed/33129364
http://dx.doi.org/10.1186/s13195-020-00710-6

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