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Effect of APOE ε4 genotype on amyloid-β and tau accumulation in Alzheimer’s disease
BACKGROUND: To assess the effects of apolipoprotein E (ApoE) ε4 genotype on amyloid-β (Aβ) and tau burden and their longitudinal changes in Alzheimer’s disease (AD) spectrum. METHODS: Among 272 individuals who underwent PET scans ((18)F-florbetaben for Aβ and (18)F-flortaucipir for tau) and ApoE gen...
Autores principales: | Baek, Min Seok, Cho, Hanna, Lee, Hye Sun, Lee, Jae Hoon, Ryu, Young Hoon, Lyoo, Chul Hyoung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603688/ https://www.ncbi.nlm.nih.gov/pubmed/33129364 http://dx.doi.org/10.1186/s13195-020-00710-6 |
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