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Directional divergence of Ep300 duplicates in teleosts and its implications

BACKGROUND: EP300 is a conserved protein in vertebrates, which serves as a key mediator of cellular homeostasis. Mutations and dysregulation of EP300 give rise to severe human developmental disorders and malignancy. Danio rerio is a promising model organism to study EP300 related diseases and drugs;...

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Detalles Bibliográficos
Autores principales: Wang, Xianzong, Yan, Junli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603692/
https://www.ncbi.nlm.nih.gov/pubmed/33129255
http://dx.doi.org/10.1186/s12862-020-01712-6