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Directional divergence of Ep300 duplicates in teleosts and its implications
BACKGROUND: EP300 is a conserved protein in vertebrates, which serves as a key mediator of cellular homeostasis. Mutations and dysregulation of EP300 give rise to severe human developmental disorders and malignancy. Danio rerio is a promising model organism to study EP300 related diseases and drugs;...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603692/ https://www.ncbi.nlm.nih.gov/pubmed/33129255 http://dx.doi.org/10.1186/s12862-020-01712-6 |