Direct conversion of human fibroblasts into dopaminergic neuron-like cells using small molecules and protein factors

BACKGROUND: Generation of neurons is essential in cell replacement therapy for neurodegenerative disorders like Parkinson’s disease. Several studies have reported the generation of dopaminergic (DA) neurons from mouse and human fibroblasts by ectopic expression of transcription factors, in which gen...

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Detalles Bibliográficos
Autores principales: Qin, Hua, Zhao, An-Dong, Sun, Meng-Li, Ma, Kui, Fu, Xiao-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603706/
https://www.ncbi.nlm.nih.gov/pubmed/33129359
http://dx.doi.org/10.1186/s40779-020-00284-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603706/
https://www.ncbi.nlm.nih.gov/pubmed/33129359
http://dx.doi.org/10.1186/s40779-020-00284-2

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