RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3

The most common genetic cause of amyotrophic lateral sclerosis (ALS) is a GGGGCC (G4C2) hexanucleotide repeat expansions in first intron of the C9orf72 gene. The accumulation of repetitive RNA sequences can mediate toxicity potentially through the formation of intranuclear RNA foci that sequester ke...

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Detalles Bibliográficos
Autores principales: Ramesh, Nandini, Daley, Elizabeth L., Gleixner, Amanda M., Mann, Jacob R., Kour, Sukhleen, Mawrie, Darilang, Anderson, Eric N., Kofler, Julia, Donnelly, Christopher J., Kiskinis, Evangelos, Pandey, Udai Bhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603783/
https://www.ncbi.nlm.nih.gov/pubmed/33129345
http://dx.doi.org/10.1186/s40478-020-01060-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603783/
https://www.ncbi.nlm.nih.gov/pubmed/33129345
http://dx.doi.org/10.1186/s40478-020-01060-y

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