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Association of polymorphisms in C1orf106, IL1RN, and IL10 with post-induction infliximab trough level in Crohn’s disease patients

BACKGROUND: Trough levels of the post-induction serum infliximab (IFX) are associated with short-term and long-term responses of Crohn’s disease patients to IFX, but the inter-individual differences are large. We aimed to elucidate whether single gene polymorphisms (SNPs) within FCGR3A, ATG16L1, C1o...

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Detalles Bibliográficos
Autores principales: Tang, Jian, Zhang, Cai-Bin, Lyu, Kun-Sheng, Jin, Zhong-Ming, Guan, Shao-Xing, You, Na, Huang, Min, Wang, Xue-Ding, Gao, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603865/
https://www.ncbi.nlm.nih.gov/pubmed/33163192
http://dx.doi.org/10.1093/gastro/goz056