Synthesis and Biopharmaceutical Characterization of Amphiphilic Squalenyl Derivative Based Versatile Drug Delivery Platform

Limited drug loading capacity (LC), mostly below 5% w/w, is a significant drawback of nanoparticulate drug delivery systems (DDS). Squalenoylation technology, which employs bioconjugation of squalenyl moiety and drug, allows self-assemble of nanoparticles (NPs) in aqueous media with significantly hi...

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Detalles Bibliográficos
Autores principales: Ho, Duy-Khiet, Christmann, Rebekka, Murgia, Xabier, De Rossi, Chiara, Frisch, Sarah, Koch, Marcus, Schaefer, Ulrich F., Loretz, Brigitta, Desmaele, Didier, Couvreur, Patrick, Lehr, Claus-Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604382/
https://www.ncbi.nlm.nih.gov/pubmed/33195079
http://dx.doi.org/10.3389/fchem.2020.584242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604382/
https://www.ncbi.nlm.nih.gov/pubmed/33195079
http://dx.doi.org/10.3389/fchem.2020.584242

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