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Effect of Kaempferol on Tacrolimus-Induced Nephrotoxicity and Calcineurin B1 Expression Level in Animal Model

BACKGROUND: The kidneys are considered one of the most susceptible organs for adverse drug effects, particularly in post-transplant conditions. Tacrolimus (FK506), a calcineurin inhibitor immunosuppressant, is an essential component in the transplantation regimen. Despite that, nephrotoxicity is a s...

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Detalles Bibliográficos
Autores principales: Ali, Ahmed Shaker, Almalki, Abdullah Saddah, Alharthy, Basma Tarek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604448/
https://www.ncbi.nlm.nih.gov/pubmed/33149706
http://dx.doi.org/10.2147/JEP.S265359