Different Human Immune Lineage Compositions Are Generated in Non-Conditioned NBSGW Mice Depending on HSPC Source

NBSGW mice are highly immunodeficient and carry a hypomorphic mutation in the c-kit gene, providing a host environment that supports robust human hematopoietic expansion without pre-conditioning. These mice thus provide a model to investigate human hematopoietic engraftment in the absence of conditi...

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Detalles Bibliográficos
Autores principales: Hess, Nicholas J., Lindner, Payton N., Vazquez, Jessica, Grindel, Samuel, Hudson, Amy W., Stanic, Aleksandar K., Ikeda, Akihiro, Hematti, Peiman, Gumperz, Jenny E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604455/
https://www.ncbi.nlm.nih.gov/pubmed/33193358
http://dx.doi.org/10.3389/fimmu.2020.573406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604455/
https://www.ncbi.nlm.nih.gov/pubmed/33193358
http://dx.doi.org/10.3389/fimmu.2020.573406

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