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Osteogenic Effect of tsRNA-10277-Loaded Exosome Derived from Bone Mesenchymal Stem Cells on Steroid-Induced Osteonecrosis of the Femoral Head

PURPOSE: Steroids are known to inhibit osteogenic differentiation and subsequent bone formation in bone mesenchymal stem cells (BMSCs). However, little is known about the role of BMSC exosomes (Exos) and tRNA-derived small RNAs (tsRNAs) in steroid-induced osteonecrosis of the femoral head (SONFH). T...

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Detalles Bibliográficos
Autores principales: Fang, Shanhong, He, Tianmin, Jiang, Jiarun, Li, Yongfeng, Chen, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604472/
https://www.ncbi.nlm.nih.gov/pubmed/33149555
http://dx.doi.org/10.2147/DDDT.S258024