S-Allylmercaptocysteine Targets Nrf2 in Osteoarthritis Treatment Through NOX4/NF-κB Pathway

PURPOSE: This study aimed to explore the potential role and mechanism of garlic-derived S-allylmercaptocysteine (SAMC), the major water-soluble fraction of garlic, in osteoarthritis (OA) both in vivo and in vitro. METHODS: The effect of SAMC in a surgical-induced OA model was examined by X-ray, stai...

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Detalles Bibliográficos
Autores principales: Yang, Guang, Sun, Shui, Wang, Jian, Li, Wei, Wang, Xianquan, Yuan, Lin, Li, Siying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604485/
https://www.ncbi.nlm.nih.gov/pubmed/33149551
http://dx.doi.org/10.2147/DDDT.S258973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604485/
https://www.ncbi.nlm.nih.gov/pubmed/33149551
http://dx.doi.org/10.2147/DDDT.S258973

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