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Chronic GPER1 Activation Protects Against Oxidative Stress-Induced Cardiomyoblast Death via Preservation of Mitochondrial Integrity and Deactivation of Mammalian Sterile-20-Like Kinase/Yes-Associated Protein Pathway

Introduction: Estrogen (17β-estradiol, E2) is well-known to induce cardioprotective effects against ischemia/reperfusion (I/R) injury. We recently reported that acute application of E2 at the onset of reperfusion in vivo induces cardioprotective effects against I/R injury via activation of its non-s...

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Detalles Bibliográficos
Autores principales: Imam Aliagan, Abdulhafiz, Madungwe, Ngonidzashe B., Tombo, Nathalie, Feng, Yansheng, Bopassa, Jean C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604496/
https://www.ncbi.nlm.nih.gov/pubmed/33193095
http://dx.doi.org/10.3389/fendo.2020.579161