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In vivo mRNA display enables large-scale proteomics by next generation sequencing

Large-scale proteomic methods are essential for the functional characterization of proteins in their native cellular context. However, proteomics has lagged far behind genomic approaches in scalability, standardization, and cost. Here, we introduce in vivo mRNA display, a technology that converts a...

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Detalles Bibliográficos
Autores principales: Oikonomou, Panos, Salatino, Roberto, Tavazoie, Saeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604504/
https://www.ncbi.nlm.nih.gov/pubmed/33037152
http://dx.doi.org/10.1073/pnas.2002650117