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Activating CD137 Signaling Promotes Sprouting Angiogenesis via Increased VEGFA Secretion and the VEGFR2/Akt/eNOS Pathway

Combination of antiangiogenesis and immunotherapy may be an effective strategy for treatment of solid tumors. Our previous work reported that activation of CD137 signaling promotes intraplaque angiogenesis. A number of studies have demonstrated that vascular endothelial growth factor receptor 2 (VEG...

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Detalles Bibliográficos
Autores principales: Li, Bo, Zhang, Yue, Yin, Runting, Zhong, Wei, Chen, Rui, Yan, Jinchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604604/
https://www.ncbi.nlm.nih.gov/pubmed/33162828
http://dx.doi.org/10.1155/2020/1649453