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Activating CD137 Signaling Promotes Sprouting Angiogenesis via Increased VEGFA Secretion and the VEGFR2/Akt/eNOS Pathway
Combination of antiangiogenesis and immunotherapy may be an effective strategy for treatment of solid tumors. Our previous work reported that activation of CD137 signaling promotes intraplaque angiogenesis. A number of studies have demonstrated that vascular endothelial growth factor receptor 2 (VEG...
Autores principales: | Li, Bo, Zhang, Yue, Yin, Runting, Zhong, Wei, Chen, Rui, Yan, Jinchuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604604/ https://www.ncbi.nlm.nih.gov/pubmed/33162828 http://dx.doi.org/10.1155/2020/1649453 |
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