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Lactate Induces Cisplatin Resistance in S. cerevisiae through a Rad4p-Dependent Process
Cisplatin is a widely used antineoplastic agent that has DNA as the main target, though cellular resistance hampers its therapeutic efficacy. An emerging hallmark of cancer cells is their altered metabolism, characterized by increased glycolysis even under aerobic conditions, with increased lactate...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604607/ https://www.ncbi.nlm.nih.gov/pubmed/33163143 http://dx.doi.org/10.1155/2020/4971525 |