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Low Incidence of Postoperative Respiratory Depression with Oliceridine Compared to Morphine: A Retrospective Chart Analysis

BACKGROUND: Oliceridine, an investigational IV opioid, is a first-in-class G-protein selective agonist at the μ-opioid receptor. The G-protein selectivity results in potent analgesia with less recruitment of β-arrestin, a signaling pathway associated with opioid-related adverse events (ORAEs). In ra...

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Detalles Bibliográficos
Autores principales: Bergese, Sergio, Berkowitz, Richard, Rider, Paul, Ladouceur, Martin, Griffith, Suzanne, Segura Vasi, Alvaro, Cochrane, Kristina, Wase, Linda, Demitrack, Mark A., Habib, Ashraf S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604609/
https://www.ncbi.nlm.nih.gov/pubmed/33163127
http://dx.doi.org/10.1155/2020/7492865