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Clustering of strong replicators associated with active promoters is sufficient to establish an early‐replicating domain
Vertebrate genomes replicate according to a precise temporal program strongly correlated with their organization into A/B compartments. Until now, the molecular mechanisms underlying the establishment of early‐replicating domains remain largely unknown. We defined two minimal cis‐element modules con...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604622/ https://www.ncbi.nlm.nih.gov/pubmed/32935369 http://dx.doi.org/10.15252/embj.201899520 |