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Clustering of strong replicators associated with active promoters is sufficient to establish an early‐replicating domain

Vertebrate genomes replicate according to a precise temporal program strongly correlated with their organization into A/B compartments. Until now, the molecular mechanisms underlying the establishment of early‐replicating domains remain largely unknown. We defined two minimal cis‐element modules con...

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Detalles Bibliográficos
Autores principales: Brossas, Caroline, Valton, Anne‐Laure, Venev, Sergey V, Chilaka, Sabarinadh, Counillon, Antonin, Laurent, Marc, Goncalves, Coralie, Duriez, Bénédicte, Picard, Franck, Dekker, Job, Prioleau, Marie‐Noëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604622/
https://www.ncbi.nlm.nih.gov/pubmed/32935369
http://dx.doi.org/10.15252/embj.201899520