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HMGB-1/RAGE signaling inhibition by dioscin attenuates hippocampal neuron damage induced by oxygen-glucose deprivation/reperfusion

Cerebral ischemia is one of the most common clinical diseases characterized by high morbidity and mortality. Neurocyte apoptosis and a cascade of inflammatory signals following cerebral ischemia-reperfusion injury (IRI) may contribute to secondary brain damage, resulting in severe neurological damag...

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Detalles Bibliográficos
Autores principales: Liu, Aijun, Zhang, Wenqian, Wang, Shuwei, Wang, Yuan, Hong, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604738/
https://www.ncbi.nlm.nih.gov/pubmed/33149785
http://dx.doi.org/10.3892/etm.2020.9361