PPM1F controls integrin activity via a conserved phospho-switch

Control of integrin activity is vital during development and tissue homeostasis, while derailment of integrin function contributes to pathophysiological processes. Phosphorylation of a conserved threonine motif (T788/T789) in the integrin β cytoplasmic domain increases integrin activity. Here, we re...

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Detalles Bibliográficos
Autores principales: Grimm, Tanja M., Dierdorf, Nina I., Betz, Karin, Paone, Christoph, Hauck, Christof R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604772/
https://www.ncbi.nlm.nih.gov/pubmed/33119040
http://dx.doi.org/10.1083/jcb.202001057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604772/
https://www.ncbi.nlm.nih.gov/pubmed/33119040
http://dx.doi.org/10.1083/jcb.202001057

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