Overexpression of RNF126 Promotes the Development of Colorectal Cancer via Enhancing p53 Ubiquitination and Degradation

BACKGROUND: RING finger protein 126 (RNF126), as a novel E3 ubiquitin ligase, plays an oncogenic role in several solid cancers. But its potential role in colorectal cancer (CRC) that harbored 50% mutant p53, to our knowledge, is rarely reported. MATERIALS AND METHODS: We investigated the clinical si...

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Detalles Bibliográficos
Autores principales: Wang, Shiyang, Wang, Tianlong, Wang, Li, Zhong, Liansheng, Li, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604871/
https://www.ncbi.nlm.nih.gov/pubmed/33149608
http://dx.doi.org/10.2147/OTT.S271855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604871/
https://www.ncbi.nlm.nih.gov/pubmed/33149608
http://dx.doi.org/10.2147/OTT.S271855

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