A silent agonist of α7 nicotinic acetylcholine receptors modulates inflammation ex vivo and attenuates EAE

Nicotinic acetylcholine receptors (nAChRs) are best known to function as ligand-gated ion channels in the nervous system. However, recent evidence suggests that nicotine modulates inflammation by desensitizing non-neuronal nAChRs, rather than by inducing channel opening. Silent agonists are molecule...

Descripción completa

Detalles Bibliográficos
Autores principales: Godin, Jean-Rémi, Roy, Patrick, Quadri, Marta, Bagdas, Deniz, Toma, Wisam, Narendrula-Kotha, Ramya, Kishta, Osama A., Damaj, M. Imad, Horenstein, Nicole A., Papke, Roger L., Simard, Alain R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604877/
https://www.ncbi.nlm.nih.gov/pubmed/31874200
http://dx.doi.org/10.1016/j.bbi.2019.12.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604877/
https://www.ncbi.nlm.nih.gov/pubmed/31874200
http://dx.doi.org/10.1016/j.bbi.2019.12.014

Ejemplares similares