CAR-T cells and TRUCKs that recognize an EBNA-3C-derived epitope presented on HLA-B*35 control Epstein-Barr virus-associated lymphoproliferation

BACKGROUND: Immunosuppressive therapy or T-cell depletion in transplant patients can cause uncontrolled growth of Epstein-Barr virus (EBV)-infected B cells resulting in post-transplant lymphoproliferative disease (PTLD). Current treatment options do not distinguish between healthy and malignant B ce...

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Detalles Bibliográficos
Autores principales: Dragon, Anna Christina, Zimmermann, Katharina, Nerreter, Thomas, Sandfort, Deborah, Lahrberg, Julia, Klöß, Stephan, Kloth, Christina, Mangare, Caroline, Bonifacius, Agnes, Tischer-Zimmermann, Sabine, Blasczyk, Rainer, Maecker-Kolhoff, Britta, Uchanska-Ziegler, Barbara, Abken, Hinrich, Schambach, Axel, Hudecek, Michael, Eiz-Vesper, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604878/
https://www.ncbi.nlm.nih.gov/pubmed/33127653
http://dx.doi.org/10.1136/jitc-2020-000736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604878/
https://www.ncbi.nlm.nih.gov/pubmed/33127653
http://dx.doi.org/10.1136/jitc-2020-000736

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