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Pre-clustering data sets using cluster4x improves the signal-to-noise ratio of high-throughput crystallography drug-screening analysis
Drug and fragment screening at X-ray crystallography beamlines has been a huge success. However, it is inevitable that more high-profile biological drug targets will be identified for which high-quality, highly homogenous crystal systems cannot be found. With increasing heterogeneity in crystal syst...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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International Union of Crystallography
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604910/ https://www.ncbi.nlm.nih.gov/pubmed/33135684 http://dx.doi.org/10.1107/S2059798320012619 |