Time-restricted feeding downregulates cholesterol biosynthesis program via RORγ-mediated chromatin modification in porcine liver organoids

BACKGROUND: Time-restricted feeding (TRF) is a dieting strategy based on nutrients availability and diurnal rhythm, shown to improve lipid metabolism efficiency. We have demonstrated previously that retinoic acid-related (RAR) orphan receptor (ROR) γ is the primary transcription factor controlling c...

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Detalles Bibliográficos
Autores principales: Zhang, Kexin, Li, Hao, Xin, Zimeng, Li, Yanwei, Wang, Xiaolong, Hu, Yun, Liu, Haoyu, Cai, Demin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604961/
https://www.ncbi.nlm.nih.gov/pubmed/33292665
http://dx.doi.org/10.1186/s40104-020-00511-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604961/
https://www.ncbi.nlm.nih.gov/pubmed/33292665
http://dx.doi.org/10.1186/s40104-020-00511-9

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