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Time-restricted feeding downregulates cholesterol biosynthesis program via RORγ-mediated chromatin modification in porcine liver organoids

BACKGROUND: Time-restricted feeding (TRF) is a dieting strategy based on nutrients availability and diurnal rhythm, shown to improve lipid metabolism efficiency. We have demonstrated previously that retinoic acid-related (RAR) orphan receptor (ROR) γ is the primary transcription factor controlling c...

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Detalles Bibliográficos
Autores principales:	Zhang, Kexin, Li, Hao, Xin, Zimeng, Li, Yanwei, Wang, Xiaolong, Hu, Yun, Liu, Haoyu, Cai, Demin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604961/ https://www.ncbi.nlm.nih.gov/pubmed/33292665 http://dx.doi.org/10.1186/s40104-020-00511-9

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