V(DD)J recombination is an important and evolutionarily conserved mechanism for generating antibodies with unusually long CDR3s

The V(DD)J recombination is currently viewed as an aberrant and inconsequential variant of the canonical V(D)J recombination. Moreover, since the classical 12/23 rule for the V(D)J recombination fails to explain the V(DD)J recombination, the molecular mechanism of tandem D-D fusions has remained unk...

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Detalles Bibliográficos
Autores principales: Safonova, Yana, Pevzner, Pavel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605257/
https://www.ncbi.nlm.nih.gov/pubmed/32948615
http://dx.doi.org/10.1101/gr.259598.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605257/
https://www.ncbi.nlm.nih.gov/pubmed/32948615
http://dx.doi.org/10.1101/gr.259598.119

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