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V(DD)J recombination is an important and evolutionarily conserved mechanism for generating antibodies with unusually long CDR3s
The V(DD)J recombination is currently viewed as an aberrant and inconsequential variant of the canonical V(D)J recombination. Moreover, since the classical 12/23 rule for the V(D)J recombination fails to explain the V(DD)J recombination, the molecular mechanism of tandem D-D fusions has remained unk...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605257/ https://www.ncbi.nlm.nih.gov/pubmed/32948615 http://dx.doi.org/10.1101/gr.259598.119 |