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Genome-wide dynamics of RNA synthesis, processing, and degradation without RNA metabolic labeling

The quantification of the kinetic rates of RNA synthesis, processing, and degradation are largely based on the integrative analysis of total and nascent transcription, the latter being quantified through RNA metabolic labeling. We developed INSPEcT−, a computational method based on the mathematical...

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Detalles Bibliográficos
Autores principales: Furlan, Mattia, Galeota, Eugenia, Gaudio, Nunzio Del, Dassi, Erik, Caselle, Michele, de Pretis, Stefano, Pelizzola, Mattia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605262/
https://www.ncbi.nlm.nih.gov/pubmed/32978246
http://dx.doi.org/10.1101/gr.260984.120