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Identification of determinants of differential chromatin accessibility through a massively parallel genome-integrated reporter assay

A key mechanism in cellular regulation is the ability of the transcriptional machinery to physically access DNA. Transcription factors interact with DNA to alter the accessibility of chromatin, which enables changes to gene expression during development or disease or as a response to environmental s...

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Detalles Bibliográficos
Autores principales: Hammelman, Jennifer, Krismer, Konstantin, Banerjee, Budhaditya, Gifford, David K., Sherwood, Richard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605270/
https://www.ncbi.nlm.nih.gov/pubmed/32973041
http://dx.doi.org/10.1101/gr.263228.120