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Identification of determinants of differential chromatin accessibility through a massively parallel genome-integrated reporter assay
A key mechanism in cellular regulation is the ability of the transcriptional machinery to physically access DNA. Transcription factors interact with DNA to alter the accessibility of chromatin, which enables changes to gene expression during development or disease or as a response to environmental s...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605270/ https://www.ncbi.nlm.nih.gov/pubmed/32973041 http://dx.doi.org/10.1101/gr.263228.120 |