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Safrole-induced expression of proinflammatory responses is associated with phosphorylation of mitogen-activated protein kinase family and the nuclear factor-κB/inhibitor of κB pathway in macrophages

OBJECTIVE: Safrole, also called shikimol and Sassafras, is the carcinogenic and phenylpropanoid compound extracted from Sassafras tree and anise, betel, and camphor. Moreover, a high concentration of safrole can be occur in the saliva because of betel nut or areca quid chewing which a common habit o...

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Detalles Bibliográficos
Autores principales: Ni, Yung-Lun, Shen, Huan-Ting, Lee, Min-Wei, Yeh, Kun-Lin, Chiang, Chen-Yu, Kuan, Yu-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605287/
https://www.ncbi.nlm.nih.gov/pubmed/33163379
http://dx.doi.org/10.4103/tcmj.tcmj_78_20